What Does ceesdekker.net Mean?
What Does ceesdekker.net Mean?
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Nanotechnology gives A selection of alternatives to add to biology. Listed here I'll current examples exactly where nanofabrication – a chance to make confined buildings with Proportions at will – is used to examine the biophysics of solitary molecules and cells. I'll current some illustrations from our lab:
Our group scientific studies bacterial cell division and is particularly aiming to represent a ‘base up biology’ in synthetic cells that may autonomously divide. Our major curiosity lies in mobile division, chromatin framework, and spatial Management.
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Nanofabrication of electrodes with sub-five nm spacing for transport experiments on solitary molecules and metallic clusters
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The coiled-coil from the human Rad50 DNA maintenance protein is made up of particular segments of amplified overall flexibility
We condition micro organism into varieties that deviate from their normal phenotype. Especially, I will show our power to form Dwell E. coli germs into novel styles for instance rectangles, squares, triangles and circles.
Dynamic ParB–DNA interactions initiate and keep a partition condensate for bacterial chromosome segregation
Imagine if, as an alternative to utilizing regular best-down silicon electronics, transistors can be created from The underside up employing one natural molecules as the switching aspects? This concept, which grew to become The premise of right now’s industry of molecular electronics, initial emerged during the 1970s.
There was one issue even though — we did not observe any measurable electrical conduction from the single polymer molecules. We concluded that at the single-molecule degree, conducting polymers have been in fact not these kinds of good conductors, which was https://www.ceesdekker.net somewhat disappointing. We So broadened our perspective to test to uncover extra promising molecules.
In 1993 he was appointed as Affiliate Professor at Delft University of Know-how. Within the mid-1990s Dekker and his workforce achieved good results with the invention of your electronic Qualities of carbon nanotubes, the first one-molecule transistor and also other nanoscience.
‘That worries the artificial cell, as Section of the Dutch BaSyC initiative. Craig Venter appeared best-down in Those people days and recognized about 5 hundred genes that are minimally essential for just a working cell. We wish to look bottom-up: how do we go from the couple of molecules to a whole Organic procedure?
Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of an individual wire bridging two electrodes
Solid-state nanopores have proven to be a remarkably versatile probe for single-molecule analysis of DNA. I'll explain several of our modern results – specifically DNA knots – as well as our endeavours to extend the abilities of reliable-condition nanopores even more, inside the path of single-protein detection, graphene nanopores, plasmonic nanopores, and DNA origami nanopores.